Tottenham Hotspur will be without star striker Harry Kane for the clash with Manchester United at Old Trafford at lunchtime on Saturday.
The 24-year-old England international has scored 13 goals in 12 games for Spurs this season, but will miss out this weekend due to a minor strain to his left hamstring.
There is no sense in taking that risk and making the problem bigger.
And, despite Kane having only found the net once in seven previous appearances against the Red Devils, Lilywhites head coach Mauricio Pochettino admits that not having his main attacker will be a major blow.
He told reporters: “The doctor and medical staff made the decision to not take the risk. There is no sense in taking that risk and making the problem bigger.
“Always you want all players available, but it is a problem. Play more or play less? Because it is most important that they are all available and fit.
“We will see afterwards for Wednesday and Real Madrid, but for tomorrow it’s impossible. We cannot take a risk, (but) it’s a minor injury, very small.
“I’m not happy, I’m disappointed, because Harry is our main striker, he’s one of the best players, not just in Tottenham, in Europe, in the world.
“Always you are going to miss your best striker. I’m not silly or stupid to talk in a different way, but that is football.”
Tottenham have been beaten on their last three visits to Old Trafford and have failed to score in the process, losing 1-0 in each of the last two seasons.
A 1-0 victory for the Red Devils on Saturday is priced at 13/2, with the hosts 13/8 to keep a clean sheet, while Romelu Lukaku is available at 20/21 to score at any time.